Health Condition 1: O135- Gestational [pregnancy-induced] hypertension without significant proteinuria, complicating the puerperium Health Condition 2: O140- Mild to moderate pre-eclampsia
Conditions
Interventions
Intervention1: Drug: Oral Labetalol starting dose of 100mg 12thhourly (Maximum 900mg/day in three divided doses)to be started if blood pressure is more than or equal to 150/100 mmHg on 2 occasions or
Sponsors
Jawahalal Nehru Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Postpartum women fulfilling all the criteria below: 1. Age more than 18years 2. Women who were antenatal diagnosed to have hypertensive disorders of pregnancy using ACOG criteria in whom the treating team intend to stop antihypertensive therapy after delivery 3. At any time before discharge from hospital blood pressure reading of a.more than or equal to 150/100 mm of Hg on 2 occasions or b.more than or equal to 160/110 mm of Hg on 1occasion
Exclusion criteria
Exclusion criteria: 1. Known case of AV heartblock 2. Heart rate 120 beats perminute 3. Serum creatinine more than or equal to 1.5mg/dl) 4. Heartfailure & pulmonary edema 5. Asthma 6. Eclampsia, HELLP syndrome 7. Critically ill on mechanical ventilation or invasive hemodynamic monitoring
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time taken to achieve blood pressure control from the initiation of the medication (Labetalol or Amlodipine).Achievement of blood pressure control will be defined defined as sustained blood pressure levels between 130-140 mm Hg systolic and 80-90mm Hg diastolic for 12 hoursTimepoint: 12 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Dose of each drug to achieve control Side effects of drugsTimepoint: 12 hours | — |
Countries
India
Contacts
Public ContactAvantika Gupta
Jawaharlal Nehru Institute of Postgraduate Medical Education and Research
Outcome results
None listed