Comparing the efficacy of Buprenorphine and Clonidine when combined with Ropivacaine in spinal anesthesia of leg surgeries.

Comparision between plain Ropivacaine, Ropivacaine with Buprenorphine and Ropivacaine with Clonidine for intrathecal use in lower limb orthopaedic surgeries - A prospective randomized controlled clinical trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/02/023197

Enrollment

Registered

2020-02-07

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M80-M85- Disorders of bone density and structure

Interventions

Intervention1: Ropivacaine: Before the beginning of surgery, 0.75% Ropivacaine 3ml (22.75 mg ) given intrathecally.Using this drug spinal anaesthesia given single shot. Control Intervention1: Buprenor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective upper limb surgeries American Society of Anaesthesiologist I or II

Exclusion criteria

Exclusion criteria: Patient refusal. Allergic to opioids/ local anaesthetics. Height 30 Patient with recent history of CVA. Coagulation disorder. Severe CVS abnormalities. Poorly controlled hypertension. Poorly controlled Diabetes mellitus. Emergency orthopaedic surgery.

Design outcomes

Primary

Measure	Time frame
To compare duration of analgesia of Ropivacaine, Buprenorphine with ropivacaine, Clonidine with ropivacaine given intrathecally in terms of first rescue analgesia requirementTimepoint: Post operative period	—

Secondary

Measure	Time frame
Time taken for onset of sensory and motor blockade. Intra operative haemodynamic changes. To determine the quality of analgesia and post operative analgesic first requiredTimepoint: Intra operative period and post operative periods	—

Countries

India

Contacts

Public ContactVasanth D

Shri sathya sai medical college and research Institute

esenkeyem@gmail.com9786743120

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026