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Photo dynamic therapy with Rose Bengal dye in patients with fungal keratitis

To observe the safety and efficacy of Photo dynamic therapy with Rose Bengal dye in patients with fungal keratitis(Pilot Project)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023188
Enrollment
5
Registered
2020-02-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H160- Corneal ulcer

Interventions

Intervention1: Photodynamic antibacterial therapy with rose bengal: All subjects with proven (Fungal keratitis) on microbiology and following the inclusion criteria will be enrolled in the study and s

Sponsors

LV Prasad Eye Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All cases with microbial keratitis with the infiltrate size between 4-6 mm with anterior to mid stromal involvement and confirmed on smears and/or culture as Fungus by Microbiologist. 2. Ready to give consent 3. Consent for regular follow-up

Exclusion criteria

Exclusion criteria: 1. Mixed infection on smears or cultures 2. Not willing to come for regular follow-up or admission or giving consent 3. Posterior stromal involvement 4. Severe fungal keratitis, with Limbal involvement 5. One eyed patient (other eye vision if less than 6/60 due to unmodifiable causes) 6. Allergic to Rose Bengal

Design outcomes

Primary

MeasureTime frame
To observe the ocular toxicity Timepoint: 1 week, 1 month, 3 month—

Secondary

MeasureTime frame
Healing of cornea ulcerTimepoint: 1 week, 1 month, 3 months—

Countries

India

Contacts

Public ContactDrBhupesh Bagga

LV Prasad Eye Institute

bhupesh@lvpei.org

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026