Spinal anaesthesia with bupivacaine with and without magnesium sulphate in patient undergoing uterus surgeries

Comparison between epidural bupivacaine with and without magnesium sulphate in patient undergoing elective total abdominal hystrectomy - A randomised controlled trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/02/023169

Enrollment

Registered

2020-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N70-N77- Inflammatory diseases of female pelvic organs

Interventions

Intervention1: Bupivacaine: Before the beginning of surgery,0.5% Bupivacaine 20ml ( 100mg ) given epidurally one time 15 minutes before incision Control Intervention1: Magnesium sulphate: Before the b

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing total abdominal hysterectomy surgery. Patients in the age group 40-60 years. ASA I & II female

Exclusion criteria

Exclusion criteria: Patient refusal. Allergy to local anesthetics/magnesium sulphate ASA III & ASA IV Coagulation disorders. Local site infection. BMI > 30. Poorly controlled Hypertension. Poorly controlled Diabetes mellitus. Severe CVS abnormalities Renal or Hepatic failure. CVS disorders like heart block,myocardial infraction

Design outcomes

Primary

Measure	Time frame
To compare the duration of analgesia of epidural block with plain Bupivacaine and Bupivacaine with Magnesium sulphate in patients undergoing total abdominal hysterectomyTimepoint: Post operative period	—

Secondary

Measure	Time frame
Onset of action Intra op requirement of analgesia Side effect-shivering, pruritis, hypotension Timepoint: Intra operative period and post operative period	—

Countries

India

Contacts

Public ContactAishwarya Guru

Shri sathya sai medical college and research institute

esenkeyem@gmail.com9786743120

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026