Hypothermia in Acute Spinal cord Injury

Evaluation of Outcome of Modest Hypothermia in Acute Spinal Cord Injury: A randomized control study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/02/023146

Enrollment

Registered

2020-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S122- Fracture of third cervical vertebra

Interventions

Intervention1: Hypothermia: core body temperature of patient will be kept at 33 celcius for 24 hours prior to surgical fixation Control Intervention1: normothermia: core body temperature of patient wi

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient of age group 18 â?? 65 years. 2. Patients with closed spinal cord injury. 3. Patients with GCS 15/15. 4. AIS score A 5. Patient willing/giving consent to take part in the study

Exclusion criteria

Exclusion criteria: 1. Age 65 years 2. AIS score B, C , D or E 3. Hyperthermia >38.5 0C on admission 4. Polytrauma patients 5. History of Severe bleeding, Coagulopathy, Thrombocytopenia 6. History of cardiac disease 7. Pancreatitis 8. History of Raynaud syndrome 9. Complete Spinal cord transection by MRI on Admission 10. Patients intubated/ sedated prior to neurological examination 11. Patients presenting to the hospital after 24 hours of injury. 12. Patient not willing to participate in study/ not giving consent.

Design outcomes

Primary

Measure	Time frame
Neurological improvement by ASIA scoringTimepoint: Day1, Day7, Day14, Day42, Day84, Day168	—

Secondary

Measure	Time frame
Pain SensitivityTimepoint: Day1, Day7, Day14, Day42, Day84, Day168	—

Countries

India

Contacts

Public ContactPrashasth B S

PGIMER

sdhatt@yahoo.com09815126600

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026