Health Condition 1: N768- Other specified inflammation of vagina and vulva
Conditions
Interventions
Intervention1: Kakrasingi _ (Pistacia integerrima Stewart ex Brandis): Fine powder of kakrasingi (1g) in capsules and will be adminstered orally twice daily for 7 days
Control Intervention1: Tab M
Sponsors
National Institute of Unani Medicine
Eligibility
Inclusion criteria
Inclusion criteria: Married women in reproductive aged (18-45 years) Patients who fulfil at least three out of the four Amsel criteria (homogenous vaginal discharge, vaginal PH > 4.5, positive whiff or amine test and presence of clue cells) to diagnose bacterial vaginosis. Patients with positive Gram stain for BV by Nugent score
Exclusion criteria
Exclusion criteria: Abnormal uterine bleeding, menstruation, frequent vaginal douche, alcohol and coumarin anticoagulants. Pregnancy and lactation, multiple sexual partners , on oral contraceptive pills and intrauterine devices. Specifc diseases such as liver disease, kidney and central nervous system diseases, blood dyscrasia, diabetes,immune defciency, and known venereal disease. History of hypersensitivity to metronidazole tablets. • Unwilling to abstain from alcohol for 3 days after treatment. Received concomitant antimicrobial therapy (topical or oral), or received a recent course (within previous 14 days) of antimicrobial or antifungal therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amsel criteria () Normal vaginal discharge, 2) negative 10% potassium hydroxide whiff test, and 3) clue cells less than 20% of total epithelial cells on microscopic examination of the vaginal wet mount using saline) after treatment.)Timepoint: 8th day (post test) | — |
Secondary
| Measure | Time frame |
|---|---|
| Microbiologic cure, defined as a Nugent score of 0â??3 Therapeutic cure, defined as meeting criteria for both clinical and microbiologic cure after treatment. Vaginal symptom scale (VSS). Timepoint: 8th day (post test) | — |
Countries
India
Contacts
Public ContactArshiya Sultana
National Institute of Unani Medicine
Outcome results
None listed