â??COMPARATIVE EVALUATION OF DIFFERENT CONCENTRATIONS OF ALCOHOL IN ULTRA-SOUND GUIDED COELIAC PLEXUS BLOCK FOR PAIN RELIEF IN UPPER ABDOMINAL CANCER PATIENTS

Comparative evaluation of different concentrations of alcohol in ultrasound guided coeliac plexus neurolysis for pain relief in patients with upper abdominal malignancies

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/023008

Enrollment

Registered

2020-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C23- Malignant neoplasm of gallbladder

Interventions

Intervention1: Alcohol USG guided celiac plexus neurolysis: Neurolysis with 30 to 40 ml of 50% alcohol will be carried out and same procedure will be performed over group B with 30 to 40 ml of 75% alc

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to give written informed consent. All patients presented with upper abdominal malignancy either sex having age between 40 and 75 years Patients of upper abdominal malignancy having pain which was not relieved by nonsteroidal anti- inflammatory drug (NSAID) or strong opioids like morphine (according to WHO ladderIII) Patients of upper abdominal malignancy developing complications on low dosages ofmorphine

Exclusion criteria

Exclusion criteria: Patients not willing to participate in the study Patient on anticoagulantiontherapy with deranged coagulation profile local or intra-abdominalinfection, sepsis and hugeascites,patients with bowel obstruction, • with physical opioid dependence and drug seeking behavior.

Design outcomes

Primary

Measure	Time frame
The intervention outcome depend upon VAS score (0-10) at weekly interval up to 12weeks. either excellent,good,satisfactory or unsatisfactory.Based on 10 cm line, the left extremity represent no pain i.e excellent outcome at all(score0)andrightextremityrepresentunbearable pain(score 10) i.e unsatisfactory outcome, the procedure will be considered successful if there will be satisfactory pain relief VAS score â?¤3 with or without morphine or reduction in the dose of morphine.Timepoint: VAS score (0-10) at weekly interval up to 12weeks i.e at 0 week,1 week,4 week,8 week and 12 week duration.	—

Measure

Time frame

The intervention outcome depend upon VAS score (0-10) at weekly interval up to 12weeks. either excellent,good,satisfactory or unsatisfactory.Based on 10 cm line, the left extremity represent no pain i.e excellent outcome at all(score0)andrightextremityrepresentunbearable pain(score 10) i.e unsatisfactory outcome, the procedure will be considered successful if there will be satisfactory pain relief VAS score â?¤3 with or without morphine or reduction in the dose of morphine.Timepoint: VAS score (0-10) at weekly interval up to 12weeks i.e at 0 week,1 week,4 week,8 week and 12 week duration.

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Secondary

Measure	Time frame
To compare the improvement in quality of life between groups. To compare the need of rescue analgesia between groups. To compare the side effect profile between groups.Timepoint: 1-24hrs	—

Countries

India

Contacts

Public ContactSarita Singh

KING GEORGE MEDICAL UNIVERSITY LUCKNOW

pragya.verma169@gmail.com8755517416

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026