To find the use of warm oxygen therapy in diabetic patients with ulcers

Effect of topical warm oxygen therapy (KADAM) in healing dynamics of diabetic foot ulcer

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/023004

Enrollment

Registered

2020-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications

Interventions

Intervention1: It is a single arm clinical trial: warm oxygen therapy will be delivered to individuals with type 2 diabetes mellitus having foot ulcers Control Intervention1: NOT APPLICABLE because it

Eligibility

Inclusion criteria

Inclusion criteria: Individuals with type 2 diabetes mellitus and non-healing diabetic foot ulcer for 3 months or more

Exclusion criteria

Exclusion criteria: foot ulcers of other pathology, individuals who are referred for surgical interventions

Design outcomes

Primary

Measure	Time frame
1. Biomarkers of wound healing, including -Matrix metalloproteinase 1, 2, 8 and 9, 2. Inflammatory markers of endothelial cells including Tumor necrosis factor Î± and Interleukin-6 3. Rate of contraction of woundTimepoint: Three time points 1.Baseline 2.After 2 weeks 3.After 8 weeks	—

Secondary

Measure	Time frame
1. Biomarkers of wound healing, including -Matrix metalloproteinase 1, 2, 8 and 9, 2. Inflammatory markers of endothelial cells including Tumor necrosis factor Î± and Interleukin-6 3. Rate of contraction of woundTimepoint: Three time points 1.Baseline 2.After 2 weeks 3.After 8 weeks	—

Countries

India

Contacts

Public ContactMegha Nataraj

Manipal College of Health Professions

arun.maiya.g@gmail.com9845350823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026