effect of Pre oxygenation on Contrast Induced Nephropathy among patients with renal dysfunction undergoing Elective Cardiovascular angiography, PCI or both in Tertiary Care Hospital in Western Maharashtra

Assessing the efficacy of Preoxygenation on Contrast Induced Nephropathy among patients with renal dysfunction undergoing Elective Cardiovascular angiography, PCI or both in Tertiary Care Hospital in Western Maharashtra– An Open Label Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/022995

Enrollment

276

Registered

2020-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N189- Chronic kidney disease, unspecified Health Condition 2: N178- Other acute kidney failure

Interventions

Intervention1: Pre oxygenation: All patients with eGFR 60 ml/min/1.73m2 who are scheduled to undergo cardiovascular angiography, percutaneous coronary intervention (PCI), or both are enrolled. The

Eligibility

Inclusion criteria

Inclusion criteria: Patients with eGFR <60 ml/min/1.73m2 who underwent elective cardiovascular angiography,PCI or both

Exclusion criteria

Exclusion criteria: a). Patient unwilling and unable to give valid informed written consent b). Acute Coronary Syndrome c). End Stage Renal Disease requiring dialysis d). Cardiogenic shock, Congestive Heart Failure e). H/o hypersensitivity to contrast media f).Chronic Obstructive Pulmonary Disease,sPO2 g). Use of antioxidant N- acetyl cysteine to prevent CIN

Design outcomes

Primary

Measure	Time frame
The primary outcome is the incidence of contrast-induced nephropathy, de ?ned as a 25% or 0.3 mg/dl increase in serum creatinine levels from baseline within 48 hours of exposure of contrast mediaTimepoint: 48 hours	—

Secondary

Measure	Time frame
NILTimepoint: NOT APPLICABLE	—

Countries

India

Contacts

Public ContactDr Inder Preet Singh Bhatia

AFMC , PUNE

tomalwar@hotmail.com9695223338

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026