Skip to content

Exosomes in PAH with and without exposure to exercise

Exosomes in pulmonary arterial hypertension with and without the exposure to exercise

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022990
Enrollment
36
Registered
2020-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I270- Primary pulmonary hypertension

Interventions

Intervention1: exercise: in addition to the standard medical treatment and patient education via the Pulmonary Hypertension Manual (PulHMan), they shall also receive an individualized, structured, hom

Sponsors

ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are diagnosed with Pulmonary Hypertension (PH) of Group 1 (acc. to WHO classification) and any functional class, stable on medical therapy for 2 months and having a tricuspid regurgitation velocity �3.4m/s with or without right ventricular dysfunction, detected on transthoracic echocardiography For the purpose of metabolomics, a discovery group comprising of 10 healthy age matched controls, free of co-morbidities shall be recruited

Exclusion criteria

Exclusion criteria: patients with neuromuscular complications limiting cardiac rehabilitation, acute coronary events, uncontrolled arrhythmias, patients on long term oxygen therapy

Design outcomes

Primary

MeasureTime frame
Circulatory metabolitesTimepoint: At baseline 3 months follow up 6 months follow up

Secondary

MeasureTime frame
6Minute Walk Test, Short Physical Performance Battery, clinical frailty score, cardiac self-efficacy, quality of life, cardiac depression scale, muscle strength, cardiac functionTimepoint: at baseline, 3 months follow up and 6 months follow up

Countries

India

Contacts

Public ContactDr Padmakumar R

Kasturba Hospital, Manipal

padmakumar69@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026