Health Condition 1: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Patients undergoing elective laparoscopic cholecystectomy will be allotted into 3 subgroups with 35 patients each and will recieve 20 mcg/kg/min (Group K1), 30 mcg/kg/min (Group K2) & 4
Sponsors
Midnapore Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age group between 18-65 years. 2) ASA grade I to II. 3) Patients posted for Elective laproscopic cholecystectomy under General
Exclusion criteria
Exclusion criteria: 1) Psychiatric disorders such as schizophrenia and acute psychoses. 2) Patients with features of raised IntraCranial Pressure 3) Penetrating Eye injury and increased IntraOcular Pressure. 4) Regular use of anti-inflammatory drugs (NSAIDs) 5) Chronic pain syndromes 6) Acute or chronic alcohol intoxication 7) Chronic kidney disease, Chronic Liver disease 8) Moderate to severe hypertension 9) Acute Porphyria 10) History of CErebroVascular accident 11) Intolerance or allergy to S(+)-ketamine 12) Any patients below 18 years old and above 65 years old 13) Any drug allergy. 14) Any emergency surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess the effectiveness of different doses of intraoperative ketamine infusion for post operative analgesia in reducing the need for rescue analgesic requirement. 2.To assess the time of requirement of first rescue analgesic dose in each individual groups.Timepoint: During the period of next 24 hours following the surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| observation of change in hemodyanamic profile in either groups upon administering of the test drugTimepoint: throughout the surgery duration | — |
Countries
India
Contacts
Public ContactBani Parvati Magda Hembrom
Dept. of Anaesthesiology, Midnapore Medical College
Outcome results
None listed