FindTrial
Sign In

Comparison of two medications Dexmedetomidine and Magnesium Sulphate for control of blood pressure and heart rate during surgery and their effects on pain relief after surgery

Comparison between intravenous Dexmedetomidine and Magnesium Sulphate on intraoperative hemodynamics and postoperative pain in lumbar spine surgeries: A randomised controlled trial - MADE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022971
Enrollment
50
Registered
2020-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M259- Joint disorder, unspecified Health Condition 2: M512- Other thoracic, thoracolumbar andlumbosacral intervertebral disc displacement

Interventions

Intervention1: Group M: Intravenous Magnesium: Bolus dose of Magnesium Sulpfate 30mg/kg in 100ml Normal Saline over 15 min followed by maintenance of 8mg/kg/hr until end of surgery. Control Interventi

Sponsors

St Johns Medical College And Hospital Bangalore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults aged 18-59 years, undergoing elective lumbar spine surgeries Either sex American physical status (ASA) I and II

Exclusion criteria

Exclusion criteria: Known history of hypersensitivity to drugs used Pregnant or lactating woman Previous spine surgeries Preexisting neuromuscular diseases or myopathy Coagulation disorders Patient on Calcium channel blockers and Beta blockers

Design outcomes

Primary

MeasureTime frame
Intraoperative hemodynamics Systolic blood pressure(SBP), Diastolic blood pressure (DBP) , Mean arterial blood pressure (MAP) and heart rate (HR) Timepoint: Every 5min for first half hour and then every 15min thereafter until end of surgery.—

Secondary

MeasureTime frame
postoperative pain by measuring numeric rating scaleTimepoint: Parameters are seen in recovery room (0 min, 30min, 1hr, 2hrs) and in ward at 4hrs, 6hrs, 8hrs, 10hrs, 12hrs.—

Countries

India

Contacts

Public ContactDr Albin Aloysius Chettanil

St Johns Medical College

drmanjula95@yahoo.com9449059395

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026