Study to assess effect of giving two different amounts of fluids through vein before surgery, on nausea and vomiting after operation

â??Effect of two preloading regimens with Ringerâ??s lactate on postoperative nausea and vomitingâ??

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/022956

Enrollment

Registered

2020-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E040- Nontoxic diffuse goiter

Interventions

Intervention1: Ringer lactate at 20ml/kg body weight: Ringer lactate at 20ml/kg body weight will be given intravenously Control Intervention1: Ringer lactate at 10ml/kg body weight: Ringer lactate at

Eligibility

Inclusion criteria

Inclusion criteria: All patients of age 18-65 years of age, undergoing surgery under general anaesthesia like thyroidectomy, breast and upper limb surgeries lasting < 3 hours

Exclusion criteria

Exclusion criteria: - Previous history of motion sickness - Obesity - Hiatus hernia - Pregnancy - Emergency cases

Design outcomes

Primary

Measure	Time frame
Assess the effect of the two preloading doses of Ringerâ??s lactate on post-operative nausea and vomiting (PONV)Timepoint: 2,6,12, 24 hours after surgery	—

Secondary

Measure	Time frame
Assess the effect of both volumes on: 1. intraoperative haemodynamics. 2. Post-operative recovery like ambulation and duration of ICU stay Timepoint: Intraoperatively every 15 minutes, then PONV will be assessed 2,6,12, 24 hours after surgery	—

Countries

India

Contacts

Public ContactDr Varsha R

Amrita Institute of Medical Sciences

sunilrajan@aims.amrita.edu09447464652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026