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Study to find out changes in heart rate and blood pressure when two different lubricants are put in nose to pass a tube to stomach

Comparison of hemodynamic changes to nasal application of lignocaine jelly versus lubricant gel and responses to Ryleâ??s tube insertion following use of both

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022945
Enrollment
40
Registered
2020-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K669- Disorder of peritoneum, unspecified

Interventions

Intervention1: Lignocaine jelly: Lignocaine jelly will be applied to nostril for insertion of Ryles tube Control Intervention1: Lubricant gel: Lubricant gel will be applied to nostril for insertion of

Sponsors

Amrita Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Patients undergoing surgical process under general anesthesia who requires insertion of a Ryles tube. - Age 20-70 years - ASA PS 1-3

Exclusion criteria

Exclusion criteria: - Allergy to local anaesthetics - patients with abnormal coagulation - Deviated nasal septum - Nasal polyps

Design outcomes

Primary

MeasureTime frame
To assess mean arterial pressure changes following nasal application of 2% lignocaine jelly versus lubricant gel for insertion of Ryleâ??s tube Timepoint: 1, 3 and 5 min after application of test drug

Secondary

MeasureTime frame
Assessment of heart rate response to nasal application of 2% lignocaine jelly versus lubricant gel and hemodynamic responses to Ryleâ??s tube insertion following use of both drugs.Timepoint: 1,3 and 3 minutes after application of test drug, after Ryles tube insertion as welll

Countries

India

Contacts

Public ContactDr Pulak Tosh

Amrita Institute of Medical Sciences

pulaktosh@gmail.com099199992

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026