Health Condition 1: F42- Obsessive-compulsive disorder
Conditions
Interventions
Intervention1: Fluvoxamine and Sertraline: Selective serotonin reuptake inhibitors
Control Intervention1: NA: NA
Sponsors
Government Medical College and Hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosis of OCD as per Diagnostic and Statistical Manual of Mental Disorders-5 2. Treatment-naïve patients 3. Those consenting to participate 4. Age group of 18-55 years 5. Any gender
Exclusion criteria
Exclusion criteria: 1. Depression, anxiety or any other psychiatric illness of diagnosable severity 2. Co-morbid intellectual disability 3. Co-morbid neurological disorder, organic brain syndrome, dementia, or epilepsy 4. Co-morbid substance dependence except caffeine and nicotine 5. Subjects with high, active suicidal risk 6. Subjects with severe medical, surgical or any other condition in which these medications are contraindicated 7. Pregnant and lactating females 8. Subjects who received ECT anytime during preceding three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To study severity of illness, neuropsychological functions and quality of life in patients with obsessive compulsive disorder. 2. To study the effect of fluvoxamine and sertraline on severity of illness, neuropsychological functions and quality of life in patients with obsessive compulsive disorder. Timepoint: Baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To study the association of socio demographic and clinical variables with severity of illness, neuropsychological functions and quality of life in patients with obsessive compulsive disorder. 2. To compare effects of fluvoxamine and sertraline on above cited parameters. Timepoint: Baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 12 weeks | — |
Countries
India
Contacts
Public ContactJasmine Brar
Government Medical College and Hospital, Chandigarh
Outcome results
None listed