A clinical trial to compare two durgs intravenous dexmeditomidine and intravenous magnesium sulphate in improving surgical field visualisation in functional endoscopic sinus surgery

Comparison of intravenous Magnesium Sulphate vs Dexmedetomidine in improving visualization of surgical field in functional endoscopic sinus surgery. A randomized controlled study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/022888

Enrollment

Registered

2020-01-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A- Magnesium Sulphate: Intravenous Magnesium Sulphate loading dose @ 40 mg/kg in 100ml NS over 10 minutes before induction. After induction, maintenance dose will be started on co

Eligibility

Inclusion criteria

Inclusion criteria: 1.Elective FESS 2.American society of anesthesiologist class I or II 3.Body mass index 18 to 30 kg/m2

Exclusion criteria

Exclusion criteria: 1. Patient having any arrhythmias-especially bradyarrhythmias and conduction block 2. Chronic hypertension 3. Allergy to Dexmedetomidine or Magnesium Sulfate 4. Patients with neuromuscular diseases 5. Psychiatric disorders 6. Cardiovascular diseases 7. Those receiving Calcium Channel Blockers 8. Long history of Diabetes Mellitus with autonomic dysfunction.

Design outcomes

Primary

Measure	Time frame
bleeding scoreTimepoint: 6 hours	—

Secondary

Measure	Time frame
hemodynamic parameterTimepoint: 6 hours;Ramsay Sedation ScoreTimepoint: 6 hours;Surgeons satisfaction scoreTimepoint: 6 hours	—

Countries

India

Contacts

Public ContactDr Sivakumar S

Pondicherry Institute Of Medical Sciences

siva85dr@gmail.com9944060676

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026