Evaluation of efficacy membrane with bone allograft in the treatment of Chronic Generalised Periodontitis Patients.

Comparative evaluation of efficacy of amniotic membrane with demineralized freeze dried bone allograft versus collagen membrane with demineralized freeze dried bone allograft in the treatment of intrabony defects â?? A clinico - radiographic study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/022883

Enrollment

Registered

2020-01-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Amniotic Membrane with Demineralized Freeze Dried Bone Allograft: The flap was reflected, the osseous defect was exposed. DFDBA was delivered in small increments into the defect. Amniot

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically healthy subjects. 2. Subjects with age between 18-60 years. 3. Patients having periodontal pockets with probing depth more than or equal to 5 mm 4. Patients suffering with chronic periodontitis requiring surgical intervention to treat an Intra bony defect adjacent to a natural tooth. 5. Patients showing radiographic evidence of infrabony osseous defect. 6. Patients who were willing to comply with all the study related procedures and who signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who were medically compromised 2. Patients with inadequate plaque control. 3. Women who were pregnant or who intended to become pregnant during the study period. 4. Oral cancer or head and neck radiation within 6 months 5. Smoking >10 cigarettes per day; daily use of smokeless tobacco, pipe, or cigar smoking 6. Untreated infection at the study site other than periodontitis. 7. Patients with any history of allergy to the material used in this study. 8. Patients who were on antibiotics or antimicrobial therapy for last 6 months 9. Patients on any drug therapy which is known to influence the periodontium. 10. Patients who have undergone any type of periodontal flap surgical procedure or regenerative therapy 6 months prior to the initial examination. 11. Patients unable to provide informed consent.

Design outcomes

Primary

Measure	Time frame
relative intrabony defect component level [rIBD]Timepoint: At Baseline and 6 Months	—

Secondary

Measure	Time frame
1. GINGIVAL INDEX (Loe and Silness in 1963) 2. PLAQUE INDEX (Turesky- Gilmore- Glickman modification of Queigly- Hein Plaque index in 1970) 3. POCKET PROBING DEPTH 4. RELATIVE CLINICAL ATTACHMENT LEVEL (rCAL)Timepoint: at baseline, 3 months, 6 months	—

Countries

India

Contacts

Public ContactEITI AGRAWAL

ITS CENTRE FOR DENTAL STUDIES AND RESEARCH

dr.rahulchopra@its.edu.in9953865327

Outcome results