Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
Conditions
Interventions
None listed
Sponsors
Tata Memorial Center
Eligibility
Inclusion criteria
Inclusion criteria: i. Confirmed diagnosis of primary breast cancer (invasive or in situ) ii. Unilateral breast cancer. iii. Patient undergone breast conservation iv. Patient planned for adjuvant radiotherapy at TMC v. Patient planned whole breast RT and tumor bed boost vi. Patient consents for photographs of both breasts vii. Non-metastatic disease viii. Age > 18 years ix. Duration between last chemotherapy cycle and radiotherapy > 2 weeks x. Ability to give written informed consent after understanding the patient information sheet xi. Willing to comply to follow up visits and scheduled assessments at TMC
Exclusion criteria
Exclusion criteria: i. Reconstructive procedure not meriting tumor bed boost ii. Patient with breast conservation not planned for tumor bed boost iii. Patients receiving weekly adjuvant radiotherapy iv. Bilateral Breast Cancer v. Male vi. Mastectomy vii. Patients undergoing partial breast irradiation viii. Patients undergoing brachy boost ix. Nipple areola complex sacrificed during surgery and reconstruction not done x. Limited life expectancy due to comorbidities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the incidence of worsening of cosmetic outcomes in breast cancer patients receiving electron and photon boostTimepoint: -Before the start of Radiotherapy -End of Radiotherapy -6 months from end of Radiotherapy -12 months from end of Radiotherapy -24 months from end of Radiotherapy | — |
Secondary
| Measure | Time frame |
|---|---|
| To study factors affecting worsening of aesthetic outcome in women receiving electron and photon boost.Timepoint: -Before the start of Radiotherapy -End of Radiotherapy -6 months from end of Radiotherapy -12 months from end of Radiotherapy -24 months from end of Radiotherapy;To compare acute and 2-year toxicity in women receiving electron and photon boost.Timepoint: -Before the start of Radiotherapy -End of Radiotherapy -6 months from end of Radiotherapy -12 months from end of Radiotherapy -24 months from end of Radiotherapy;To correlate cosmetic outcome (both subjective and objective) with body image, breast pain and rib painscales of the EORTC-BR 23 quality of life.Timepoint: -Before the start of Radiotherapy -End of Radiotherapy -6 months from end of Radiotherapy -12 months from end of Radiotherapy -24 months from end of Radiotherapy;To study temporal trends in patient reported outcome with respect to aesthetic assessmentTimepoint: -Before the start of Radiotherapy -End of Radiotherapy -6 months from end of Radiotherapy -12 months from end of Radiotherapy -24 months from end of Radiotherapy;To validate the Body Image Scale in Indian breast cancer patientsTimepoint: -Before the start of Radiotherapy -End of Radiotherapy -6 months from end of Radiotherapy -12 months from end of Radiotherapy -24 months from end of Radiotherapy | — |
Countries
India
Contacts
Public ContactDr Tabassum Wadasadawala
Tata Memorial Center, Mumbai
Outcome results
None listed