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Effect of single dose of steroid on postoperative sore throat,nausea vomiting and pain in patients undergoing breast surgeries

Effect of single dose of IV dexamethasone on the incidence of post-operative sore-throat nausea, vomiting and pain in patients undergoing breast surgeries- A Randomized control trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022829
Enrollment
50
Registered
2020-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50-C50- Malignant neoplasms of breast

Interventions

Intervention1: Group D: In addition to induction drugs Group D patients will receive 8mg of single dose intravenous dexamethasone. Control Intervention1: GroupC: Standard general anaesthesia protocol

Sponsors

Amrita Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18ââ?¬â??60 years, of the American Society of Anaesthesiologists (ASA) physical status 1ââ?¬â??2, undergoing breast surgeries lasting 2-3h under general anaesthesia with laryngeal mask airway will be included in this study.

Exclusion criteria

Exclusion criteria: Patients with an anticipated difficult airway, history of allergy to the test drug, who required more than one attempt at insertion and those with pre-operative sore throat or already on analgesics or steroids (systemic or inhaled) will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
Primary objective is to assess the reduction in incidence and severity of postoperative sore throat in patients undergoing breast surgery under general anaesthesia with laryngeal mask airway in patients.Timepoint: 0,2,4,12,24h in the postoperative period

Secondary

MeasureTime frame
Secondary objectives include reduction in incidence of postoperative hoarseness of voice,cough,PONV,pain score and postop analgesic requirement.Timepoint: 0,2,4,12,24 h in the postoperative period

Countries

India

Contacts

Public ContactNitu PV

Amrita Institute of Medical Sciences

nituveesundeep@gmail.com09495962020

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026