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Comparing nerve block and systemic pain relievers for pain relief following total knee replacement

Continuous adductor canal block versus systemic analgesics in postoperative analgesia following unilateral total knee arthroplasty â?? a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022825
Enrollment
42
Registered
2020-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Continuous adductor canal bock: Continuous adductor canal bock with 30 ml of 0.5ï¼?Ropivacaine with 1mcg/ml fentanyl followed by 0.2% Ropivacaine and I mcg/ml Fentanyl at 5ml/hr adduct

Sponsors

MOSC Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA I-III 2.Body mass index 20 - 35kg/m2 3.Advanced osteoarthritis of the knee joint â??Kellgren and Laurence stage III and IV 4.Total knee replacements with cruciate retaining implants 5.Willingness to take part in the study

Exclusion criteria

Exclusion criteria: 1.Known allergy to the study drugs 2.Contraindication to Neuraxial blockade and Adductor canal block 3.Patients with cognitive impairment 4.Preexisting neuropathy on operating limb 5.Uncontrolled cardiovascular / hepatic / renal disease 6.Osteoarthritis of the knee joint with significant bone loss requiring bone grafts or augments during total knee arthroplasty 7.Significant osteoarthritis on the opposite knee or other joints which can affect the mobility of the patient.

Design outcomes

Primary

MeasureTime frame
Post operative analgesia determined with visual analogue scores for painTimepoint: 6,12,18,24 and 48 hours postoperatively

Secondary

MeasureTime frame
Level of patient satisfaction and Length of hospital stayTimepoint: at the time of discharge;quadriceps muscle strength using Medical Research Council Scale and to assess the adverse eventsTimepoint: 24 and 48 hours postoperatively

Countries

India

Contacts

Public ContactDr Shaloo Ipe

MOSC Medical College

shaloo_ipe@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026