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A clinical trial to study the effects of two treatment modalities, steroid ointment versus combined phototherapy with steroid ointment for patients with chronic hand eczema

A left-right comparison of combination of UV A 1 phototherapy with topical steroids versus topical steroids in treatment of moderate-severe chronic hand eczema: a randomized open label trial with blinded outcome assessment.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022819
Enrollment
21
Registered
2020-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L259- Unspecified contact dermatitis, unspecified cause

Interventions

Intervention1: Combination of phototherapy with topical steroid: Medium dose UVA1 phototherapy thrice weekly on alternate day for 6 weeks plus Beclomethasone diproprionate 0.025% ointment daily for 2

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with bilateral chronic hand eczema (duration > 6 months), either episodic or continuous Moderate- severe nature on both hands, with HECSI score of atleast 17 in each hand

Exclusion criteria

Exclusion criteria: 1.Patients with associated nail pits or distal onycholysis 2. Concurrent chronic erythematous plaques over bony points and scalp 3.Patients with pustules on the palms in the past/present 4.Potassium hydroxide mount positivity 5.Pregnant and lactating mothers 6.Patients with history of Cancer, radiotherapy 7. Patients on or taken systemic immunosuppressants or phototherapy within the previous 4 weeks

Design outcomes

Primary

MeasureTime frame
Change in HECSI (Hand Eczema Severity Index) Change in VAS (Visual Analogue Scale) for pruritus Timepoint: at 6 weeks and at 6 months

Secondary

MeasureTime frame
Change in PGA (Physician Global Assessment) Time to disease remission Time to disease relapse Side effects of therapy Timepoint: at 6 weeks and at 6 months

Countries

India

Contacts

Public ContactDr Sivaranjini R

JIPMER

siva11rsamy@yahoo.com9994085511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026