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Compare the pain releif benefit of Ultrasound guided abdominal plane nerve block and standard pain releief technique in patients following cesarean delivery and its relation with OXTR gene

A randomized controlled study comparing the ultrasound-guided Transversalis fascia plane block and standard multimodal analgesia technique utilizing wound infiltration for post-caesarean pain management and mRNA expression of OXTR gene

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022813
Enrollment
60
Registered
2020-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Patients will receive bilateral Ultrasound-guided Transversalis fascia plane block at the end of the surgery: Patients will receive bilateral Ultrasound-guided Transversalis fascia plan

Sponsors

University College Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA grade I or II undergoing lower segment caesarean section with pfannenstiel incision under subarachnoid block

Exclusion criteria

Exclusion criteria: Patients having other causes of chronic pain,Patients having cognitive dysfunction or inability to comprehend various questionnaires, Patients having chronic neurological disorders/substance abuse,body mass index (BMI) > 40 kg/m2

Design outcomes

Primary

MeasureTime frame
To determine and compare the time to first request of analgesia between the two groupsTimepoint: The Time to first request of analgesia will be measured from completion of the intervention i.e. wound infiltration or abdominal plane block following the completion of surgery till the patients first demand for analgesia

Secondary

MeasureTime frame
NRS pain score at rest and movement, Total consumption of diclofenac in 24 hours, Pain detect questionnaire (PDQ), NPSI scores, SF-12 score, Incidence of CPSPTimepoint: Incidence of CPSP at the end of 14th week and rest all parameters at the end of 1st, 6th and 12th, 24th hour and then at the end of 6th week, 10th week, and 14th week.

Countries

India

Contacts

Public ContactDiksha Gaur

University College Of Medical Sciences and GTB Hospital

geetanjalidr@yahoo.co.in09818392246

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026