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Effect of ropivacaine on pain relief in patients of brain surgery

A study to evaluate the efficacy of ropivacaine wound instillation through surgical drain for postoperative analgesia in patients undergoing supratentorial craniotomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022806
Enrollment
44
Registered
2020-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA 1 to 3 patients posted for elective supratentorial craniotomy under general anaesthesia

Interventions

Intervention1: ropivacaine wound instillation: ropivacaine instilled through surgical drain and VAS score seen at extubation and at 1, 2, 4, 8, 24 hr after extubation for requirement of rescue analges

Sponsors

Department of anaesthesiology and critical care Pt BDSharma PGIMS UHS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 to 3 patients undergoing elective supratentorial craniotomy under general anaesthesia

Exclusion criteria

Exclusion criteria: Patients having Glasgow coma scale (GCS) Inability to communicate or comprehend, Known to local anaesthetics allergy, Previous history of craniotomy, Planned for postoperative ventilator support, History of drug/alcohol abuse were excluded

Design outcomes

Primary

MeasureTime frame
EVALUATE THE EFFICACY OF ROPIVACAINE WOUND INSTILLATION FOR POSTOPERATIVE ANALGESIATimepoint: VAS score will be noted at extubation and at 1, 2, 4, 8, 24 hrs after extubation and time for 1st analgesic dose required noted

Secondary

MeasureTime frame
heart rate,systolic bood pressure,diastolic blood pressure, mean arterial pressure,spO2,Etco2,RASS score, Modified aldrete score will be notedTimepoint: The parameters will be recorded at baseline, at extubation, at 1, 3, 5, 10min after extubation and for 24hrs at 1, 2,4, 8, 24 hrs after extubation

Countries

India

Contacts

Public ContactDr Kiran Mittal

PGIMS,UHS,Rohtak

khawahishmittal@gmail.com7404955686

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026