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To observe the effect of low blood pressure on brain oxygenation

Effect of permissive hypotension on cerebral oxygen saturation during trans-sphenoidal surgery in controlled hypertensive patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/01/022763
Enrollment
30
Registered
2020-01-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G978- Other intraoperative and postprocedural complications and disorders of nervous system

Interventions

Intervention1: Nil: Nil

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Controlled hypertensive patients with BP <140/90mmHg(ASA2) undergoing elective trans sphenoidal surgery.

Exclusion criteria

Exclusion criteria: Hematocrit H/o is ischemic cardiovascular disease and conduction defects, H/o cerebrovascular disease and suspected neurological deficits, Hepatic and renal insufficiency, Patients on antipsychotic drugs, H/o bleeding disorder or on anticoagulant therapy, Known hypersensitivity to drug.

Design outcomes

Primary

MeasureTime frame
To assess the cerebral oxygen saturation ScO2 by using Near Infrared Spectroscopy during controlled hypotension in controlled hypertensive patients undergoing elective trans sphenoidal surgery.Timepoint: intraoperative period—

Secondary

MeasureTime frame
To assess postoperative cognitive dysfunctionTimepoint: 7 days after surgery—

Countries

India

Contacts

Public ContactDr VKeerthana

Post Graduate Institute of Medical Education and Research Chandigarh

bhartineerja@yahoo.com9915575145

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026