Health Condition 1: O- Medical and Surgical
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The aim of the study will be to study the effect of one-lung ventilation on the right ventricular function since one-lung ventilation causes acute changes in right ventricular afterload which may affect right ventricular function. Adult patients of either sex, undergoing elective lung resection surgeries (segmentectomies, lobectomies, pneumonectomies)will be recruited into the trial and the effects of one lung ventilation on right ventricular deformation will be studied by 2-dimensional strain echocardiography, since strain echocardiography represents a load-independent measure of ventricular function. Also right and left ventricular function will be assessed with 3-dimensional echocardiography.
Exclusion criteria
Exclusion criteria: Emergency surgery; obese patients; patients having arrhythmias; contraindications to transesophageal echocardiography probe placement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in right ventricular function after one-lung ventilationTimepoint: Baseline before induction; immediately after intubation; 15 minutes after one-lung ventilation; 2 hours after one-lung ventilation; at skin closure | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative atrial fibrillationTimepoint: 72 hours postoperatively | — |
Countries
India
Contacts
AIIMS Bhubaneswar