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Effects of one-lung ventilation on right ventricular function

The effects of one-lung ventilation on right ventricular deformation:an intraoperative echocardiographic study using 2-dimensional strain imaging in patients undergoing lung resection surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/01/022759
Enrollment
80
Registered
2020-01-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

AIIMS Bhubaneswar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The aim of the study will be to study the effect of one-lung ventilation on the right ventricular function since one-lung ventilation causes acute changes in right ventricular afterload which may affect right ventricular function. Adult patients of either sex, undergoing elective lung resection surgeries (segmentectomies, lobectomies, pneumonectomies)will be recruited into the trial and the effects of one lung ventilation on right ventricular deformation will be studied by 2-dimensional strain echocardiography, since strain echocardiography represents a load-independent measure of ventricular function. Also right and left ventricular function will be assessed with 3-dimensional echocardiography.

Exclusion criteria

Exclusion criteria: Emergency surgery; obese patients; patients having arrhythmias; contraindications to transesophageal echocardiography probe placement

Design outcomes

Primary

MeasureTime frame
Changes in right ventricular function after one-lung ventilationTimepoint: Baseline before induction; immediately after intubation; 15 minutes after one-lung ventilation; 2 hours after one-lung ventilation; at skin closure

Secondary

MeasureTime frame
Incidence of postoperative atrial fibrillationTimepoint: 72 hours postoperatively

Countries

India

Contacts

Public ContactDr Satyajeet Misra

AIIMS Bhubaneswar

misrasatyajeet@gmail.com9438884048

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026