Health Condition 1: G403- Generalized idiopathic epilepsy and epileptic syndromes
Conditions
Interventions
Intervention1: Intramuscular Midazolam versus intranasal Midazolam: Comparison of efficacy of single intramuscular Midazolam
0.2mg/kg versuss single dose of intranasal Midazolam at 0.2 mg/kg in abort
Sponsors
Government Medical College and Hospital Aurangabad
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children in age group of 6 months to 12 years with active seizures without I. V. access 2. Patients with written valid and informed consent obtained from their parents
Exclusion criteria
Exclusion criteria: 1. Child who received emergency treatment for present seizures from elsewhere 2. Child with clinically significant psychiatric disorder 3. Children with upper respiratory tract infection and profuse nasal discharge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abortion of motor component of acute seizure activityTimepoint: Time of abortion of ongoing seizure at 5 min and 10 min | — |
Secondary
| Measure | Time frame |
|---|---|
| - To observe side effects on vital parameters of patients after drug administration (intramuscular and intranasal midazolam) - To observe recurrence of seizure (within 1 hr of administration of drug) - To observe the need for use of second anti-epileptic drug Timepoint: Abortion of ongoing seizure activity at 5 min and 10 min and recurrence of seizure within 60 min and effect on pulse, respiratory rate and blood pressure at 5 min and 10 min. | — |
Countries
India
Contacts
Public ContactDr Amit Tukaram Patil
Department of Paediatrics
Outcome results
None listed