Health Condition 1: G248- Other dystonia
Conditions
Interventions
Intervention1: Low frequency repetitive transcranial magnetic stimulation (rTMS): Low frequency (1 Hz) rTMS protocol will be given to patients with writers cramp, satisfying the inclusion criteria.
He
Sponsors
All India Institute of Medical SciencesAIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: a) Diagnosis of isolated, task specific focal hand dystonia as per MDS consensus update on phenomenology and classification of dystonia by 2 independent movement disorder specialists. b) Not received botulinum toxin injections in the past 4 months c) No local scalp infections/ wounds d) Able to give informed consent
Exclusion criteria
Exclusion criteria: a) History of brain tumor, stroke, traumatic brain injury, epilepsy or seizure in lifetime. b) History of major depression, psychosis c)Implanted pacemaker, intracardiac lines, pumps or stimulators, or metallic foreign bodies inside the eye or skull. (Dental fillings and braces are allowed) d) Pregnancy (negative UPT in 2 weeks)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline in Writers cramp rating scale (WCRS) Timepoint: After 5 sessions of each of real and sham stimulations | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Group-wise changes in functional connectivity on resting state and task-based fMRI between the groups- REAL stimulation and SHAM stimulation 2. Improvement in handwriting assessed using videography and goniometer 3) Patient reported subjective improvement on Likert scaleTimepoint: After 5 sessions of each of real and sham stimulations | — |
Countries
India
Contacts
Public ContactDr SEETHA LEKSHMI B
All India Institute of Medical Sciences (AIIMS), New Delhi
Outcome results
None listed