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Comparative Evaluation of Typical Vs Atypical antipsychotics in the treatment of stable Schizophrenia

Comparative Evaluation of Typical Antipsychotic Haloperidol with Atypical Antipsychotics Olanzapine, Risperidone and Aripiprazole in the Treatment of Stable Schizophrenia in a Tertiary Care Teaching Hospital at Dehradun, Uttarakhand

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/01/022712
Enrollment
98
Registered
2020-01-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F209- Schizophrenia, unspecified Health Condition 2: null- Stable Schizophrenic patients

Interventions

Control Intervention1: Haloperidol, Olanzapine, Aripiprazole, Risperidone: Comparison of typical antipsychotic Haloperidol with atypical antipsychotics Olanzapine, Aripiprazole and Risperidone

Sponsors

Dr Subhash Vishal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Stable schizophrenic with initial BPRS score of >= 24, Clinical Global Impression Severity Rating Scale >= 4

Exclusion criteria

Exclusion criteria: Age less than 18 or more than 70; pregnant or lactating women, acute emergencies, patients with impaired hepatic or renal function; any systemic illness; history of hypersensitivity / allergy to any of the drugs included in study

Design outcomes

Primary

MeasureTime frame
All of three atypical antipsychotics olanzapine, aripiprazole and risperidone were found to be more effective as well as safer in terms of changes in BPRS, PAN-SS, CGI and CDRS scores as compared to typical antipsychotic haloperidol.Timepoint: 01.01.2015 - 31.12.2015—

Secondary

MeasureTime frame
No secondary outcome(s)Timepoint: Not applicable—

Countries

India

Contacts

Public ContactDr Subhash Vishal

SGRR Institute of Medical & Health Sciences

sushreesoham@gmail.com8006643025

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026