Effect of Vitamin B12 supplementation in diabetic patients

Effect of Vitamin B12 supplementation on glycaemic control in uncontrolled hyperhomocysteinemic type 2 diabetic patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/022711

Enrollment

Registered

2020-01-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Vitamin B12: (DRUG GROUP) will receive Methylcobalamin 500 ug daily with usual antidiabetic therapy for 4 weeks Control Intervention1: antidiabetics: CONTROL GROUP will be given require

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age between 30 -70 years 2.Sex: Male/ Non-lactating female 3.HbA1 > 8 4.Serum Homocysteine > 15 umol / L 5.Patient with IHD

Exclusion criteria

Exclusion criteria: 1. Age 2. Pregnancy 3. Lactating mother 4. Patient with Insulin dependent Diiabetes Mellites 5. Severe and Complicated diabetes 6. Patient with hepatic or renal dysfunction

Design outcomes

Primary

Measure	Time frame
To compare the change in HbA1c and blood sugar levels with Vitamin B12 supplementation in poorly controlled type 2 diabetic patientsTimepoint: baseline and 4 weeks	—

Secondary

Measure	Time frame
To compare the change in lipid profile, blood pressure with vitmain B12 supplementation in poorly controlled type 2 diabetic patientsTimepoint: Baseline and 4 weeks	—

Countries

India

Contacts

Public ContactDr Yogendra N Keche

Smt Kashibai Navale Medical College and Hospital

drynkeche@gmail.com08805018398

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026