Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications
Conditions
Interventions
Intervention1: Low Dose Subarachnoid block (Spinal anaesthesia): Patients randomised to this group will receive 1ml of 0.5% hyperbaric bupivacaine (5 mg) and 0.5 ml of 25 μg fentanyl (total volume of
Sponsors
Jawaharlal Institute of Postgraduate Medical Education and Research JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: Patients with diabetic foot infection posted for Emergency below knee amputation surgery
Exclusion criteria
Exclusion criteria: Patients who are in vasopressor/inotropic support. Patients who are in coagulopathy (INR > 1.5 or platelet Patients with Systolic BP less than 80 mm Hg. Patients who are unable to cooperate for the procedure. Local infection at procedural site. Patients who are allergic to local anesthetics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of percentage decrease in systolic blood pressure (SBP) from the baseline between the two groups (Group low dose subarachnoid block and Group femoral-popliteal block)Timepoint: Baseline, every two minutes for first 10 minutes after intervention and every 5 minutes till the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of mean intra-operative fluid used between the groupsTimepoint: From the intervention to the end of surgery, amount of intravenous fluid administered will be documented;Comparison of mean vasopressor use intra-operatively (to maintain a minimum MAP of 65 mm-Hg) between the groups. Timepoint: From the intervention to the end of surgery, requirement of vasopressor will be documented;Comparison of pH, pCO2, lactate and bicarbonate between the groupsTimepoint: Before the intervention and at the end of surgery | — |
Countries
India
Contacts
Public ContactMuthapillai Senthilnathan
Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
Outcome results
None listed