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Comparison between oral clonidine and oral pregabalin tablet on vitals during operation and pain duration after laproscopic gall bladder operation

A comparative study between oral clonidine and oral pregabalin on perioperative haemodynamic response and post operative analgesia in patients undergoing laparoscopic cholecystectomy under general anaesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/01/022685
Enrollment
60
Registered
2020-01-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: Oral tablet: Haemodynamic changes Post operative analgesia Level of Sedation will be assessed upto 24 hours postoperatively and duration of study is around 1 year Control Intervention

Sponsors

JLN Medical college and hospital Ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients of ASA grade I and II aged between 18 and 60 years of either sex posted for laparoscopic cholecystectomy surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: ASA grade III and above. Age 60 years. Patients with severe systemic disease like IDDM, uncontrolled hypertension, kidney and liver disease, severe respiratory disease. Seizure disorder. Coronary artery disease or recent history of MI. Anticipated difficult intubation. Body weight >100 kg or obese. Pregnant and lactating women. Mentally impaired patients. Patients of psychiatric disorders and sleep disorders. Patients on steroids since last 6 months. Hypersensitivity to study drugs.

Design outcomes

Primary

MeasureTime frame
Haemodynamic changes Timepoint: 1 year

Secondary

MeasureTime frame
Post operative analgesia Level of Sedation Any significant side effects or complications. Timepoint: 1 year

Countries

India

Contacts

Public ContactDr Veena mathur

Jawahar lal nehru medical college, Ajmer

veenamathur41@gmail.com949460517947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026