Health Condition 1: L80- Vitiligo
Conditions
Interventions
Intervention1: Electrofulguration assisted dermabrasion: Electrofulguration of the patch will be done using hyfrecator at monoterminaland low output mode using the ball tipped electrode bent at 30 deg
Sponsors
Department of Dermatology Venereology and Leprology PGIMER
Eligibility
Inclusion criteria
Inclusion criteria: Clinical diagnosis of segmental or non segmental vitiligo 2 independent patchesbof 3x 3 cm size each present symmetrically or unilaterally over the same part or a single patch ofvsize 6x6 cm Stable leaions for more than 1 year Disease is not responding to medical therapy for 12 weeks or residual patches post medical therapy
Exclusion criteria
Exclusion criteria: Pregnancy and lactation History of unstable cardiac diseasevor pacemakers Patients with active disease VIDA more than 1 History of hypertrophic scars or keloid Skin infection Patients with unrealistic expectations History of bleeding disorders Patients on anticoagulants Immunosuppressed patients Patients still in wash off period of therapy that is 4 weeks for topical and 12 weeks for systemic therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the percentage of patients achieving 75 percent repigmentation with respect to the two different methods at 24 weeks of follow up post treatmentTimepoint: 0 4 8 12 16 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess whether the extent of repigmentation has any correlation to the expression levels of growth factors which are SCF, bFGF, endothelin 1Timepoint: 0 4 8 12 16 24 weeks;To evaluate the repigmentation patterns of the lesions pre and post post procedure by dermoscopy and to ennumerate the dermatoscopic markers of repigmentation as well markers of success of the procedureTimepoint: 0 4 8 12 16 24 weeks | — |
Countries
India
Contacts
Public ContactAnubha Dev
Department of Dermatology, PGIMER, Chandigarh
Outcome results
None listed