The patients with head and neck cancer develop respiratory complications due to disease itself or the effects of chemoradiation. Inspiratory Muscle Training strengthens diaphragm and reduces respiratory complications. This study evaluates the effect of IMT on the cardiorespiratory parameters.

Effect of Inspiratory Muscle Training on diaphragm mobility, thickness and cardiorespiratory function in patients with head and neck cancer.

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/01/022649

Enrollment

Registered

2020-01-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: INSPIRATORY MUSCLE TRAINING (IMT): The subjects will perform the manoeuvre over 7 weeks using the Threshold IMT device with a frequency of one session per day for 5 days a week. The sub

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with head and neck cancer stage III, IVa, IVb receiving chemoradiation therapy (radical). 2.Patients of either gender. 3.Patients above 18 years of age.

Exclusion criteria

Exclusion criteria: 1.Patients with head and neck cancer who have previously undergone a surgical treatment. 2.Patients with severe trismus. 3.Patients with any artificial airways. 4.Patients unable to perform the procedure. 5.Any previous diaphragmatic dysfunction or neuromuscular disease which could cause an impact over the evaluation.

Design outcomes

Primary

Measure	Time frame
Diaphragm mobility (in cms) Diaphragm thickness (in cms) MIP (in cm H2O) MEP (in cm H2O) FEV1 (in %) FVC (in %) FEV1/FVC 6-MWT (6-MWD in m)Timepoint: All the outcome measures will be evaluated before the start of chemoradiation therapy (baseline) and after 7 weeks of chemoradiation therapy.	—

Secondary

Measure	Time frame
NOT APPLICABLETimepoint: NOT APPLICABLE	—

Countries

India

Contacts

Public ContactDrStephen Samuel

Manipal Academy of Higher Education

stephen.samuel@manipal.edu

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026