Health Condition 1: - Health Condition 2: - Health Condition 3: N20- Calculus of kidney and ureter
Conditions
Interventions
Intervention1: Intramuscular injection of dexmedetomidine: Single dose of 1 microgram/kg intramuscular dexmedetomidine
Control Intervention1: normal saline: Single dose of equal volume of Intramuscula
Sponsors
Nizams institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients scheduled for elective PCNL procedures, ASA grade 1&2 and age 18-60 years
Exclusion criteria
Exclusion criteria: pregnancy, renal failure, patients on analgesics, rate controlled drugs, seizure disorders, patient on antidepressants / antipsychotics, unwillingness to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the role of IM dexmedetomidine in alleviating the catheter related bladder symptoms based on visual analogue pain scale. To evaluate the inflammatory response as evidenced by fever, tachycardia, total WBC count, ESR Timepoint: intubation response at 1,5,10 mim and immediately after extubation. CRBS and inflammatory responseon day 0. 1,2 and 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| Intubation response Sedation score by Ramsay sedation scale Adverse effect like bradycardia and hypotension: Timepoint: Base line Before IM inj 30 min after IM Inj 1 min after Intubation 5 min 10 min After extubation | — |
Countries
India
Contacts
Public ContactNirmala Jonnavithula
Nizams Institute of Medical Sciences
Outcome results
None listed