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A clinical trial to see the effects of two different preparations of platelet rich plasma (PRP) on baldness and under eye dark circles

A split scalp and face study to evaluate the effects of Platelet Rich Plasma (PRP) prepared and activated by two different methods in Androgenetic Alopecia and Periorbital hyperpigmentation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/12/022556
Enrollment
45
Registered
2019-12-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L648- Other androgenic alopecia

Interventions

Intervention1: Platelet Rich Plasma (PRP)prepared by standard double spin method: Intra-lesional injections of PRP prepared by the standard double spin method and activated by calcium over one half of

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES JODHPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients having androgenetic alopecia. 2. Patients having periorbital hyperpigmentation

Exclusion criteria

Exclusion criteria: 1. Patients with known platelet dysfunction syndrome 2. Patients with platelet counts less than 1 lac/microlitre 3. Patients with chronic medical illness, malignancy, systemic illness 4. Patients with active infection at the procedure site 5. Patients on anticoagulant therapy 6. History of keloid formation 7. Patient with fever 8. Patient using systemic corticosteroid or injectable corticosteroid at local site 9. Patients receiving any other modality for hair growth or depigmentation

Design outcomes

Primary

MeasureTime frame
To standardize and simplify the technique of platelet rich plasma (PRP) preparation and activation and utilize it in reversing androgenetic alopecia and periorbital hyperpigmentationTimepoint: 6 months—

Secondary

MeasureTime frame
To assess the effects of PRP in periorbital hyperpigmentationTimepoint: 6 months;To assess the levels of angiogenic and antiangiogenic factors like PDGF, VEGF, TGF Ã?² and Endostatin in PRP by ELISA Timepoint: 6 months;To see the regenerative and angiogenic effects of PRP in Androgenic alopeciaTimepoint: 6 months—

Countries

India

Contacts

Public ContactANIL BUDANIA

ALL INDIA INSTITUTE OF MEDICAL SCIENCES JODHPUR

anilbuddy25@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026