Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium
Conditions
Interventions
Intervention1: drug intervention.: the study includes comparison between 2 drugs
single dose of intravenous magnesium sulphate 50 mg/kg as i/v infusion in 100ml NS 10 minutes prior to cesarean section and single intravenous dose of dexamethasone 8mg in 100 ml NS 10 minutes prior t
Sponsors
BPS GMC W
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA physical status I & II pregnant females posted for elective and emergency caesarean section. 2.Pregnant females giving informed written consent.
Exclusion criteria
Exclusion criteria: 1.Patient refusal for the study. 2.History of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic diseases. 3.History of allergy to drugs under study. 4.History of treatment with magnesium or calcium channel blockers(e.g. pregnancy induced hypertension and eclampsia.) 5.History of opioid, steroid or analgesic abuse. 6.History of diabetes mellitus Type 1 or 2, peptic ulcer disease, glaucoma, hypertension, fungal or viral infection12. 7.Cases of spinal anaesthesia which get converted into general anaesthesia due to any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of the study is to evaluate postoperative anslgesic effect of singlevdose of intravenous magnesium sulphate infusion versus singledose of dexamethasone infusion for postoperative analgesia in patients undergoing caesarean section under spinal anaesthesia.Timepoint: 1.To determine the duration of sensory blockade and motor blockade in each group. 2.To determine the hemodynamic parameters in each group. 3.To determine the time of first liquid intake postoperatively by the patient after advised nil per oral period. 4.APGAR score of the baby at 1 and 5 minutes to assess the overall neonatal outcome. 5.To determine side effects, if any, in each group. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 To determine the duration of sensory blockade and motor blockade in each group. 2 To determine the hemodynamic parameters in each group. 3 To determine the time of first liquid intake postoperatively by the patient after advised nil per oral period. 4 APGAR score of the baby at 1 and 5 minutes to assess the overall neonatal outcome. 5 To determine side effects, if any, in each group. Timepoint: 1Haemodynamic monitoring related to each group intraoperatively at 0 min and at 5 minute interval upto 1 hrs and postoperatively at 0hrs,1 hr, 2hr, 3hr, 4hr,6hr,8hr,12hr,18hr,24hrs respectively. | — |
Countries
India
Contacts
Public Contactishrat yousuf
BPS Govt medical college for women
Outcome results
None listed