Health Condition 1: J384- Edema of larynx
Conditions
Interventions
Intervention1: intravenous Dexamethasone: One group will receive Inj Dexamethasone 0.5 milligram/kg/dose 2 doses prior to extubation at 6 hours interval and 2 doses post extubation.(-12 hrs, -6 hrs, 0
Sponsors
All India Institute of Medical sciences Raipur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children admitted in the PICU and requiring airway stabilization and mechanical ventilation. 2. Duration of intubation more than 24 hours and not exceeding 14 days.
Exclusion criteria
Exclusion criteria: 1). Vocal cord anomalies and other anatomic abnormalities of the upper airways beforeintubation 2). Previous use of corticosteroids during hospitalization within the past 7 days. 3). Clinical contraindication for the use of corticosteroids. 4).Surgical trauma to the upper airway. 5).A history of previous upper airway obstruction ( subglottic stenosis) 6). Patients with pseudobulbarpalsy 7). Spontaneous extubation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stridor score more than or equal to 4 requiring intubationTimepoint: 0 6 12 24 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| CLR MTV SOFA scoreTimepoint: 0 6 12 24 48 hours | — |
Countries
India
Contacts
Public ContactDr Atul Jindal
All India Institute of Medical Sciences,Raipur
Outcome results
None listed