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To compare norepinephrine and phenylephrine infusion to prevent spinal anesthesia induced hypotension

Prophylactic efficacy of norepinephrine and phenylephrine infusion against spinal hypotension during lower segment caesarean section:A randomised double-blind controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/12/022505
Enrollment
190
Registered
2019-12-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O295- Other complications of spinal andepidural anesthesia during pregnancy

Interventions

Intervention1: Prophylactic infusion of Norepinephrine for control of spinal hypotension: Norepinephrine infusion 5microgram/min iv is started just after spinal anaesthesia in patients undergoing lowe

Sponsors

Vijayanagar Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anesthesiologists physical status 2 2.Singleton term pregnancy

Exclusion criteria

Exclusion criteria: 1.Age less than 18 years 2.Height less than 150cm or more than 180cm 3.Weight less than 50kg or more than 100kg 4.Contraindication to spinal anaesthesia 5.Allergy to drugs used in the study 6.Eclampsia,preeclampsia,placenta previa,diabetes mellitus,hypertension,cardiovascular disease or refusal to be in the study

Design outcomes

Primary

MeasureTime frame
Incidence of hypotensionTimepoint: Study parameters are observed and recorded just before spinal anaesthesia and thereafter every minute after spinal anaesthesia until 10 min after baby extraction

Secondary

MeasureTime frame
Incidence of hypertension, APGAR score of the baby, bradycardia, tachycardia, nausea and vomittingTimepoint: Study parameters are observed and recorded just before spinal anaesthesia and thereafter every minute after spinal anaesthesia until 10 min after baby extraction

Countries

India

Contacts

Public ContactDr Pachha Priya

Vijayanagar Institute of Medical Sciences

drsrinivasd@gmail.com9845224880

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026