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Neuropathic Pain in Cranio-vertebral Junction Anomalies

Central neuropathic pain in craniovertebral junction anomalies

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/12/022489
Enrollment
40
Registered
2019-12-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G890- Central pain syndrome

Interventions

Intervention1: Pregabline: 75 mg BD Route of Administration-Per Oral Duration-Followed up for 3 months Control Intervention1: Carbamazepine: 100 mg TDS For one week then 200 mg TDS Route of Administr

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: The patients with CVJ anomaly diagnosed on the basis clinical features, confirmed by CT or MRI will be included.

Exclusion criteria

Exclusion criteria: Pregnant mother, children ( < 15 years), patients with history of drug allergy, renal or hepatic failure, malignancy, coexistent stroke, head injury or spinal trauma, major psychiatric illness, on immune or chemotherapy, painful neuropathy due to any cause, and those unwilling for consent will be excluded

Design outcomes

Primary

MeasureTime frame
Reduction in VAS score by 50% will be considered as improvementTimepoint: 1 and 3 months

Secondary

MeasureTime frame
1. Reduction in allodynia in 2. Quantitative sensory Testing (QST) 3. Side Effect Improvement in sleep Timepoint: 1 and 3 months

Countries

India

Contacts

Public ContactJayantee Kalita

Department of Neurology, SGPGIMS

jayanteek@yahoo.com9450411673

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026