FindTrial
Sign In

Depth of Invasion in oral cancer - Is clinical examination valid?

Validation of Clinical measurement of depth of invasion for staging in Oral Cancer patients according to 8th AJCC

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/12/022485
Enrollment
50
Registered
2019-12-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C069- Malignant neoplasm of mouth, unspecified

Interventions

Intervention1: Measurement of Depth of Invasion: Newly diagnosed patients of Squamous Cell Carcinoma oral cavity â?? oral tongue and buccal mucosa with T1-3 lesions and presenting to Surgical Oncology

Sponsors

All india Institute of Medical Sciences Bhubaneswar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Histopathologicalevidence of squamous cell carcinoma in oral cavity. 2. Patients giving consent for the planned oral surgery. 3. Clinically T1- T3 lesions as per AJCC 8th edition

Exclusion criteria

Exclusion criteria: 1. Tumors of other than squamous histology. 2. Patients who have receivedChemotherapy/ Radiation therapy 3. Patients having undergone excision biopsy 4. Not undergone MRI as imaging modality 5. Patients with second primary tumors. 6. Patients refusing to give consent.

Design outcomes

Primary

MeasureTime frame
To establish the correlation between clinical and histopathological assessment of depth of invasion in case of oral cancer.Timepoint: 1. Clinical Assesment Before Surgery 2. After Imaging 3. After Resection/Surgery 4. After Fixation of Specimen—

Secondary

MeasureTime frame
To estimate the extent of tumor shrinkage in formalin fixed specimen. Timepoint: 1. After Resection/Surgery 2. After Fixation of Specimen ;To estimate the surgical margin shrinkage in formalin fixed specimen.Timepoint: 1. Intraoperatively 2. After Resection/Surgery 3. After Fixation of Specimen;To study the correlation between pattern of invasion with grade of disease, nodal status and final stage of the disease.Timepoint: 1. Clinical Assesment Before Surgery 2. After Imaging 3. After Fixation of Specimen—

Countries

India

Contacts

Public ContactMahesh Sultania

All india Institute of Medical Sciences, Bhubaneswar

drmaheshsultania@gmail.com9999330769

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026