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Assessment of pain during drug injection when the drug is warm and cold in comparison with warm and cold intravenous fluid

A comparative study on the effect of carrier fluid and propofol temperature on reducing propofol injection pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/12/022468
Enrollment
144
Registered
2019-12-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services

Interventions

Intervention1: propofol: 200ml of either warm or cold carrier fluid will be infused over 5 mins, then 20mg of inj propofol 1% wil be given intravenously over 10secs along with carrier fluid.

Sponsors

MS Ramaiah Medical College and hospitals
Lead Sponsor
Dr Rasheeda Fayazi
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: patients undergoing elective surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: Allergy to propofol Inability to comprehend Verbal Rating Scale (VRS) Pregnant and breastfeeding women Peripheral neuropathy Patients with skin disease or erythema

Design outcomes

Primary

MeasureTime frame
To assess the incidence and degree of pain during Propofol injection using warm or cold propofol with heated or cold carrier fluid.Timepoint: immediately after intervention—

Secondary

MeasureTime frame
To observe hemodynamic changes during propofol injection at different temperatures.Timepoint: baseline, pre-induction, immediately after intervention, every minute for three minutes—

Countries

India

Contacts

Public ContactDr Rasheeda Fayazi

MS Ramaiah Medical College

drvinayak_ps@yahoo.co.in9900859460

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026