Effect of an adjunct to routine mechanical debridement in treating gum disease

Photodynamic therapy using zinc oxide photosensitizer as an adjunct to scaling and root planing in the management of chronic periodontitis - a split mouth double blind randomized controlled clinical trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/12/022458

Enrollment

Registered

2019-12-20

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: zinc oxide gel: Zinc oxide gel used in the current study would be synthesized using â??green chemistry approachâ??. It would be prepared using hydrothermal technique with Zinc acetate a

Eligibility

Inclusion criteria

Inclusion criteria: Patients of good systemic health and Presence of a minimum of 20 teeth and at least one site with probing pocket depth (PPD) of 4-7 mm and clinical attachment level (CAL) of 2 mm or greater, in each of the four quadrants.

Exclusion criteria

Exclusion criteria: Patients who have undergone periodontal therapy during the previous 6 months of commencement of the study. Subjects on antibiotics or immunosuppressant medication 6 months prior to the study. Chronic Smokers, Alcoholics, Smokeless tobacco users. Subjects with acute illnesses/acute intraoral lesions. Pregnant women and lactating mothers. Medically compromised subjects.

Design outcomes

Primary

Measure	Time frame
Porphyromonas gingivalis in subgingival plaque by Real-time PCR.Timepoint: Baseline (before commencement of periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.	—

Secondary

Measure	Time frame
Gingival bleeding index (Ainamo and Bay., 1975)Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.;Gingival index (Loe H. and Silness P., 1963)Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.;Plaque index (Sillness P.and Loe H., 1964)Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.;Probing pocket depth and clinical attachment level.Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.	—

Measure

Time frame

Gingival bleeding index (Ainamo and Bay., 1975)Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.;Gingival index (Loe H. and Silness P., 1963)Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.;Plaque index (Sillness P.and Loe H., 1964)Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.;Probing pocket depth and clinical attachment level.Timepoint: Baseline (before commencement of Periodontal treatment), end of 1 month and end of 3 months following periodontal treatment.

—

Countries

India

Contacts

Public ContactDr Veena H R

KLE Societys Institute of Dental Sciences

drveenahr@gmail.com9480516011

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026