FindTrial
Sign In

Determining the correlation between echocardiographic blood flow velocity changes and breath holding maneuver to evaluate whether a hypotensive patient on ventilator support will be benefitted by further intravenous fluid therapy

Use of pulmonary arterial velocity time integral variation and effect of inspiratory pause in predicting fluid responsiveness in acute circulatory failure

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/12/022450
Enrollment
101
Registered
2019-12-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system

Interventions

None listed

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES NEW DELHI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Mechanically ventilated patients of age 18 years and more admitted in the ICU. 2.Patients with Acute circulatory failure â?? presence of any one of the following. -Systolic blood pressure -Need of vasopressors to maintain systolic blood pressure > 90 mmHg. -Urine output -Heart rate > 100 /min

Exclusion criteria

Exclusion criteria: Patients not in sinus rhythm Patients with low tidal volumes (less than 6 ml/kg) Patients with known cardiac valvular dysfunction Right heart failure Patients with very high respiratory rate (HR/RR Morbid obesity-BMI >=35 kg/m2 Poor echocardiographic window

Design outcomes

Primary

MeasureTime frame
To evaluate the correlation between pulmonary arterial velocity time integral variation, aortic velocity time integral variation and inspiratory pause maneuver to predict fluid responsiveness in mechanically ventilated patients with acute circulatory failure.Timepoint: 1 day—

Secondary

MeasureTime frame
To determine sensitivity, specificity, positive predictive value and negative predictive value of pulmonary arterial velocity time integral variation, aortic velocity time integral variation and inspiratory pause maneuver to predict fluid responsiveness in mechanically ventilated patients with acute circulatory failure.Timepoint: 1 day—

Countries

India

Contacts

Public ContactShanmugam R

All India Institute of Medical Sciences, New Delhi

dilipshende@gmail.com8800377697

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026