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Comparison of two types of radiotherapy plans (SIB-IMRT and 3D-CRT) in treatment of breast cancer undergoing breast conservation surgery by evaluation of doses to the target and normal tissues.

Dosimetric comparison of simultaneous integrated boost with intensity modulated radiotherapy (SIB-IMRT) versus three dimensional conformal radiotherapy (3D-CRT) in breast conservation therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/12/022419
Enrollment
30
Registered
2019-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

None listed

Sponsors

Rohini Khurana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: KPS > 70. HPE : Infiltrating Ductal Carcinoma(IDC). Patints undergoing BCS and ALND/SLNB with negative margins. Surgical clips mandatory.

Exclusion criteria

Exclusion criteria: HPE other than IDC. Synchronous and/or metachronous malignancy. Distant metastasis. Internal mammary node positivity. Previous thoracic irradiation. Patient undergoing oncoplstic/breast augmentation surgeries. Unfit/unwilling to undergo radiotherapy

Design outcomes

Primary

MeasureTime frame
To evaluate dosimetric parameters in SIB-IMRT versus 3D-CRT following breast conservation surgery in terms of target volume coverage and organ at risk doses.Timepoint: 12 months—

Secondary

MeasureTime frame
To evaluate acute and late toxicities by 3D-CRT based treatment and its correlation with dosimetric parameters.Timepoint: 18 months—

Countries

India

Contacts

Public ContactRohini Khurana

DR. Ram Manohar Lohia Institute of Medical Sciences

poojariavinash96@gmail.com9494194735

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026