Mechanical ventilation is normally used for patients who are undergoing laparoscopic surgeries under general anesthesia. Volume control ventilation is a mode used in ventilator settings. The purpose of study is to compare two different ratios of volume control ventilation

Comparison of volume controlled ventilation 1:1 (Inspiratory :Expiratory -I:E) ratio with 1:2(I:E) ratio in upper abdominal laparoscopic surgeries- a prospective randomized control trial.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/12/022418

Enrollment

Registered

2019-12-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system

Interventions

Intervention1: Group A: 38 patients with VCV (1:1) ratio: Patient will be pre oxygenated with 100% O2, General anaesthesia will be induced with midazolam (30-50 mcg/kg), Fentanyl (2mcg/kg), Propofol (

Eligibility

Inclusion criteria

Inclusion criteria: 1)American society of anaesthesiologist (ASA) classification 1 and 2 2)Body mass index not more than 35

Exclusion criteria

Exclusion criteria: 1)Chronic Obstructive Lung Disease & Bronchial Asthma 2)Patients with Coronary Artery Disease

Design outcomes

Primary

Measure	Time frame
peak inspiratory pressure (Ppeak) and mean inspiratory pressure (Pmean) in VCV 1:1 (I: E) ratio Vs 1:2(I: E) ratio ventilationTimepoint: 2 HOURS	—

Secondary

Measure	Time frame
Hemodynamics (Systolic blood pressure, diastolic blood pressure, mean arterial pressure, Heart rate, SPO2,ETCO2) in VCV 1:1(I: E) ratio with 1:2(I: E) ratio Timepoint: 2 HOURS	—

Countries

India

Contacts

Public ContactDr Mamie Zachariah

Pondicherry Institute of Medical Sciences

mamiezac@gmail.com8344252595

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026