Assessment of combined efficacy of gargling with drakshaguloochyadi and chewing with khadiradi vati in curative intended radiotherapy induced xerostomia in head and neck cancer

Assessment of combined efficacy of drakshaguloochyadi kavala and khadiradi vati mukhadharana in curative intended radiotherapy induced xerostomia in head and neck cancer A clinical study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/12/022396

Enrollment

Registered

2019-12-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R682- Dry mouth, unspecified

Interventions

Intervention1: Drakshaguloocyadi kavala and khadiradi vati mukhadharana: From 1st day of treatment drakshaguloochyadi kashaya is given for kavala and khadiradi vati for chewing thrice daily for 1 mont

Eligibility

Inclusion criteria

Inclusion criteria: Patients underwent radiotherapy diagnosed with head and neck cancer suffering from xerostomia Patient presenting with symptoms of dry mouth like difficulty in chewing and swallowing Impairment in sense of taste and smell and difficulty in talking Patients having unstimulated whole saliva flow rate less than 0.3ml/min and stimulated whole saliva flow rate less than 1ml/min

Exclusion criteria

Exclusion criteria: Patients diagnosed with sjogrens syndrome Patients diagnosed with diabetes mellitus Patients diagnosed with any other systemic diseases having dryness of mouth Patients having other oral diseases like oral mucositis and oral ulcers

Design outcomes

Primary

Measure	Time frame
Questionnaire to assess xerostomiaTimepoint: 1st day 31st day	—

Secondary

Measure	Time frame
Sialometry pH of saliva Timepoint: 1st day 31st day	—

Countries

India

Contacts

Public ContactDr K Sivabalaji

Amrita school of ayurveda

balajisiva85k@gmail.com7559027947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026