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Comparison of two drugs in post operative pain management in breast surgeries

â??COMPARATIVE EFFICACY OF LEVOBUPIVACAINE AND ROPIVACAINE IN ULTRASOUND GUIDED SERRATUS ANTERIOR PLANE BLOCK FOR PATIENTS UNDERGOING UNILATERAL BREAST SURGERIES: A RANDOMIZED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/12/022389
Enrollment
44
Registered
2019-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: R20-R23- Symptoms and signs involving the skin and subcutaneous tissue

Interventions

Intervention1: INJ LEVOBUPIVACAINE BY ULTRASOUND GUIDED SERRATUS ANTERIOR PLANE BLOCK: Single bolus dose of 30ml of 0.5% INJ LEVOBUPIVACAINE, IS ADMINISTERED BY ULTRASOUND GUIDANCE FOR SERRATUS ANTERI

Sponsors

Vijayanagar institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I & II patients Female patients in the age group of 18 to 65 years. Patients posted for elective unilateral breast surgeries with or without axillary clearance under general anaesthesia.

Exclusion criteria

Exclusion criteria: Refusal by patients for the block. Surgery duration more than 2 hours. History of significant systemic disorders (cardiovascular, respiratory, central nervous system or renal system). Infection at block site of block. Thoracic wall and chest wall deformities. Allergy to the study drugs.

Design outcomes

Primary

MeasureTime frame
To compare the duration of postoperative analgesiaTimepoint: Study parameters are observed and recorded just before the administration of block, 5 minutes after administration, at the time of skin incision and every 10 minutes intra-operatively following the block till extubation and post-operatively at 5 min, 15min, 30min, then hourly for first 2 hours and at 4,6,12,24hrs after extubation. Post-operative pain will be assessed using visual analog scale (VAS) at rest and at coughing. Inj.tramadol 50 mg IV is used as rescue analgesic when VAS score is 4.

Secondary

MeasureTime frame
the need for rescue analgesic, total dose of rescue analgesic required, perioperative haemodynamics incidence of post-operative nausea and vomiting (PONV) and adverse effects, if any.Timepoint: Up to 24hrs after extubation

Countries

India

Contacts

Public ContactDr Krishna Rathod

Vijayanagar institute of medical sciences, Ballari

halsanadu@gmail.com9980600724

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026