To compare the levels of bacteria in patients with gum disease by treating with two different antibiotics after tooth cleaning.

Comparative estimation of levels of P. gingivalis in subgingival plaque following application of Doxycycline gel and Moxifloxacin gel as an adjunct to scaling and root planing in chronic periodontitis patients: A Randomized Control Trial.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/12/022381

Enrollment

Registered

2019-12-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: MOXIFLOXACIN GEL: SINGLE SUB GINGIVAL APPLICATION OF 0.4% MOXIFLOXACIN GEL ONE WEEK AFTER SCALING AND ROOT PLANING Intervention2: DOXYCYCLINE GEL: SINGLE SUB GINGIVAL APPLICATION OF 8.8

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with minimum complement of 20 teeth. Subjects who are diagnosed with the presence of interproximal probing pocket depth (PPD/CAL) of >= 5mm after phase 1 therapy in an asymptomatic tooth.

Exclusion criteria

Exclusion criteria: Subjects who had undergone any periodontal treatment in the past 6 months. Subjects diagnosed with Aggressive periodontitis Subjects who are smokers. Subjects who have received antibiotics/ anti-inflammatory drugs/ steroids in past 6 months. Pregnant and lactating women. Subjects with history of cardiac diseases, malignancy or any other inflammatory disorders.

Design outcomes

Primary

Measure	Time frame
EXPECTING REDUCTION IN P. gingivalis COUNT, REDUCTION IN PROBING POCKET DEPTH AND GAIN IN CLINICAL ATTACHMENT LEVEL.Timepoint: BASELINE, 1 MONTH AND 3 MONTHS	—

Secondary

Measure	Time frame
EXPECTING GRADUAL REDUCTION IN P. gingivalis COUNT, REDUCTION IN PROBING POCKET DEPTH AND GAIN IN CLINICAL ATTACHMENT LEVEL.Timepoint: BASELINE, 1 MONTH AND 3 MONTHS	—

Countries

India

Contacts

Public ContactDr JAYAPRAKASH G S

COORG INSTITUTE OF DENTAL SCIENCES

jayaprakashgadagi@gmail.com9972912662

Outcome results