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Effect of fentanyl administered at different time intervals on induction dose of propofol using bispectral index monitor

Effect of fentanyl administered at different time intervals on induction dose of propofol using bispectral index monitor

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/12/022377
Enrollment
60
Registered
2019-12-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: N200- Calculus of kidney Health Condition 3: H712- Cholesteatoma of mastoid Health Condition 4: C509- Malignant neoplasm of breast of unspecified site Health Condition 5: H058- Other disorders of orbit Health Condition 6: N209- Urinary calculus, unspecified

Interventions

Intervention1: Group II: Titrated propofol intravenous after 3 minutes of stat intravenous 2 mcg/kg intravenous fentanyl injection Intervention2: Group III: Titrated propofol intravenous after 5 minut

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I/II Duration of surgery > 1 hour

Exclusion criteria

Exclusion criteria: ASA III or more Haemodynamic instability Allergy to Propofol or fentanyl

Design outcomes

Primary

MeasureTime frame
Propofol requirement in mgTimepoint: At the end of induction when BIS reaches 60

Secondary

MeasureTime frame
Additional Propofol requirement due to vocalisation,bucking,any other reasonTimepoint: After Bis Value reaches 60;Bis Value recorded that was less than or equal to 60Timepoint: At the time Bis Value reaches 60;Heart rate,Blood Pressure,SpO2Timepoint: Every 1 minute till the time Bis Value reaches 60;Induction timeTimepoint: From the time Propofol starts till BIS value reaches 60;Side Effects like hypotension,bradycardia and interventions.Timepoint: From start of Propofol till BIS value reaches 60

Countries

India

Contacts

Public ContactChristopher Dass

AIIMS,New Delhi

cdcdcd25@gmail.com9560177416

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026