Abdominal hysterectomy is major surgery.post operative pain is common.pain after surgery can be reduced by giving drugs before surgery with pregabalin tab before surgery. Giving 1 drug or giving with combination decreases pain after surgery and decreases other analgesic dose requirement.

Comparative study of premedication with pregabalin or pregabalin with paracetamol for post operative pain control in abdominal hysterectomy patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2019/12/022366

Enrollment

Registered

2019-12-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified

Interventions

Control Intervention1: PREGABALIN AND PREGABALIN WITH PARACETAMOL. COMPARED WITH CONTROL GROUP.: Group P1. Given pregabalin 150 mg 1 hour prior to surgery Group P2. Given pregabalin 150 mg with parace

Eligibility

Inclusion criteria

Inclusion criteria: 90 patients in 3 groups of 30 each.ASA 1 and 2 Group P1 premedicated with pregabalin 150 mg Group P2 premedicated with pregabalin 150 mg with paracetamol 500 mg Group P3 no premedication given

Exclusion criteria

Exclusion criteria: 1.patient with known allergy to medicine 2.hysterctomy done under general Anaesthesia 3.ASA 3 and above

Design outcomes

Primary

Measure	Time frame
To assess the pain after surgery ..to compare post operative pain in controland in study group.Timepoint: Immediate post surgery to first 24 hours	—

Secondary

Measure	Time frame
Premedication decreases total analgesic doses post op for first 24 hours. To see for any side effects associated with premedicant drugsTimepoint: Pain and sedation score assessed from immediate post op to first 24 hours	—

Countries

India

Contacts

Public ContactPREMA

IGMC SHIMLA

ajay_5644@yahoo.com9418028130

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026